-
Using Gene Editing, Neuroscientists Develop a New Model for Autism
By introducing a gene variant associated with autism into monkeys, researchers hope to use the model to study treatment options for severe neurodevelopmental disorders. Using the genome-editing system CRISPR, researchers at MIT and in China have engineered macaque monkeys to express a gene...
-
Communication in Brain May Be Remarkably Constant in Autism
Communication in brain activity in people with autism are unusually consistent over seconds — and even years, two new studies suggest.1,2 One study shows that patterns of connectivity remain stable in autistic adolescents, whereas they tend to change and specialize in controls. The other study...
-
New Biomarker Panel Could Accelerate Autism Diagnoses
About 17 percent of kids with autism identified with metabolic blood test Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder...
-
Inherited Variations in Noncoding Sections of DNA Associated with Autism
A new study has identified an association between paternally-inherited rare structural variants in noncoding segments of genes and the development of autism spectrum disorder (ASD). The study, funded in part by the National Institute of Mental Health (NIMH) and published in Science, adds to a...
-
Researchers Link Increased Infant Brain Fluid to Autism
MRIs show a brain anomaly in nearly 70 percent of babies at high risk of developing the condition who go on to be diagnosed, laying the groundwork for a predictive aid for pediatricians and the search for a potential treatment. A national research network led by UNC School of Medicine’s Joseph...
-
Simons Foundation: Funder of Basic Science Research, Early Mover in Autism Science
In 2003, Simons Foundation co-founders Marilyn and Jim Simons set out to understand the state of autism science. Having recently awarded a grant or two to scientists working in autism genetics, they were eager to understand how the field as a whole was faring. They convened a small gathering of...
-
“Give a Spit” to Help Scientists Uncover the “Female Protective Effect” for Autism
For years, we’ve known that four times as many boys as girls are diagnosed with autism. More recently, genetic research has surprisingly shown that the various genes that cause autism are equally distributed in boys and girls. So what explains this difference - why do some girls who have the...
-
What Happened to All the Females with Autism Spectrum Disorders?
The concept of an autistic disorder is generally accepted to have originated with Leo Kanner and his classic 1943 account of ‘Autistic Disorders of Affective Contact’ (Kanner, 1943). He described 11 children with what would now be regarded as severe autism. Three of these 11 were girls, and as...
-
Integrating ABA into Practice: Addressing the Misconceptions
The past few decades has seen drastic changes to the field of autism, at least in part due to changes in the defining characteristics/diagnostic criteria for Autistic Spectrum Disorder (ASD).1 As a result of increasingly inclusive criteria, professionals in fields such as psychiatry, medicine,...
-
Evidence-Based Practice for Very Young Children with Autism: Delivering Family-Centered Services within a Community Programs
Evidence from randomized controlled trials supports the efficacy of naturalistic developmental behavioral interventions (NDBIs; Schreibman et al., 2015) for young children with autism spectrum disorder (ASD). The Early Start Denver Model (ESDM; Rogers & Dawson, 2010) and Early Social...
